BDBM19855 Balicatib::CHEMBL371064::N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)::N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(4-propylpiperazin-1-yl)benzamide::basic piperazine-containing compound, 10
SMILES CCCN1CCN(CC1)c1ccc(cc1)C(=O)NC1(CCCCC1)C(=O)NCC#N
InChI Key InChIKey=LLCRBOWRJOUJAE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 19855
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of human recombinant CatB assessed as suppression of enzyme-mediated Z-Arg-Arg-AMC cleavage by QFRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of cathepsin B in human HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nM EC50: 61nMpH: 6.0 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair